You might have heard of this before and even have had people swear to you that it works. But like most things, not everything works for everyone. Most toothpaste contains triclosan which dehydrates a pimple and thus dries them out. All you need to do is to take a bit of toothpaste and dab it on the pimple. However, this should be considered an emergency remedy only because along with your pimple, the toothpaste might even dry your skin out.